Stem Cell & Regenerative Medicine

Cell and Genetic Therapy

Cell therapy is aimed at treating diseases by restoring or modifying certain sets of cells or by using cells to carry physical therapy. Cell and genetic therapy are innovative medical approaches that aim to treat or cure diseases by targeting the cellular and genetic levels. In cell therapy, living cells, often derived from the patient or a donor, are introduced into the body to repair or replace damaged tissues, regenerate healthy cells, or boost the immune system's ability to fight disease, as seen in CAR-T cell therapies for cancer. Genetic therapy, on the other hand, involves altering the genetic material within a person's cells to correct defective genes, deactivate harmful ones, or introduce new genes for therapeutic benefits. This can be achieved through techniques like CRISPR-Cas9 or viral vectors. These therapies hold significant promise for treating a wide range of conditions, including genetic disorders, cancers, and degenerative diseases, offering more targeted and potentially curative options. With cell therapy, cells are implanted or transplanted outside the body before being injected into a patient. Cells may originate from the patient (independent cells) or donor (allogeneic cells).Genetic therapy aims to treat diseases by replacing, , shutting down or introducing genes to cells— either internally (in vivo) or externally (ex vivo). Other therapies are considered to be genetic and genetic therapies. These therapies work by changing the the genes in certain cell types and inserting them into the body.