Stem Cell & Regenerative Medicine

Cancer Stem Cells & Targeted Therapeutics

Cancer stem cells (CSCs) drive tumor growth, metastasis, and therapy resistance, making them critical targets in regenerative oncology. This session explores mechanisms regulating CSC self-renewal, differentiation, and interaction with the tumor microenvironment. Therapeutic strategies focus on selective targeting of CSCs using gene editing, immunotherapy, and nanomedicine-based drug delivery systems. Biomarkers and molecular profiling enable precision interventions, minimizing off-target effects and enhancing treatment efficacy. Regenerative principles are applied to restore normal tissue architecture post-therapy, reduce recurrence, and promote organ function. Preclinical and clinical studies demonstrate efficacy in hematological malignancies, solid tumors, and metastatic cancers. Attendees will examine innovative techniques, translational challenges, and future directions in CSC-targeted regenerative oncology.