Stem Cell & Regenerative Medicine

ell-Based Therapies for Neurological Disorders

Cell-based therapies have emerged as a promising approach for treating neurological disorders, offering the potential to repair damaged tissues, restore lost function, and improve quality of life for patients. These therapies involve the transplantation or manipulation of cells to replace or support damaged neurons or neural tissue. Stem cells, including embryonic stem cells and induced pluripotent stem cells (iPSCs), have the ability to differentiate into various cell types, including neurons and glial cells. These cells can be used to replace damaged or lost cells in the central nervous system (CNS). Neural stem cells (NSCs) are a type of stem cell found in the CNS that can differentiate into neurons, astrocytes, and oligodendrocytes. Transplantation of NSCs has shown promise in conditions such as Parkinson's disease, spinal cord injury, and stroke. Mesenchymal stem cells (MSCs) are multipotent cells found in various tissues, including bone marrow and umbilical cord tissue. MSCs have immunomodulatory and anti-inflammatory properties, making them a potential treatment for neuroinflammatory disorders such as multiple sclerosis.